Because there were no obvious morphological and biochemical characteristics of adipocytes in prostate cancer tissues induced by intraprostatic injection of LNCaP cells stably transfected with SFMBT2 shRNA (data not shown), we decided to examine infiltration of preadipocytes, which may play an important role in prostate and breast cancer metastasis [33,34,35,36]. This evidence concerns the gene SFMBT2 and Familial prostate cancer.