Because there were no obvious morphological and biochemical characteristics of adipocytes in prostate cancer tissues induced by intraprostatic injection of LNCaP cells stably transfected with SFMBT2 shRNA (data not shown), we decided to examine infiltration of preadipocytes, which may play an important role in prostate and breast cancer metastasis [33,34,35,36]. The gene discussed is SFMBT2; the disease is prostate carcinoma.