SDH abnormalities are associated with a tumorigenesis risk, including the development of PGLs/PCCs, renal and thyroid cancer, as well as composite PGLs/gastrointestinal stromal tumors (GISTs)/pulmonary chondromas (Carney triad) and PGLs/GISTs (Carney–Stratakis syndrome) [42]. Here, SDHB is linked to thyroid cancer.