SSRP1 and hepatocellular carcinoma: As a result, transfection of miR-4784 mimics reduced the luciferase activity of SSPR1-Wt, while transfection of miR-4784 mimics did not alter the luciferase activity of SSRP1-Mut in HCC cells (Figure 4(b)), confirming a direct interaction between miR-4784 and SSRP1 mRNA.