To gain insight into the interactions of genes, lncRNAs and pathways associated with VVD, we screened 30 DE genes in eight pathways (the Jak-stat signaling pathway, Toll-like receptor signaling pathway, Wnt-signaling pathway, mTOR signaling pathway, VEGF signaling pathway, Notch signaling pathway, TGF-beta signaling pathway, and Fanconi anemia pathway), which are related to immunity and skeleton development. This evidence concerns the gene SOAT1 and Fanconi anemia.