Through KEGG analysis, we focused on the following signaling pathways related to skeletal development and immunity: the Jak-stat signaling pathway, Toll-like receptor signaling pathway, Wnt-signaling pathway, mTOR signaling pathway, VEGF signaling pathway, Notch signaling pathway, TGF-beta signaling pathway and Fanconi anemia pathway (S6-3 Table). The gene discussed is MTOR; the disease is Fanconi anemia.