Furthermore, AST has great therapeutic value for lung disease, such as an antifibrotic effect against the promotion of myofibroblast apoptosis based on dynamin-related protein-1 (Drp1)-mediated mitochondrial fission in vivo and in vitro [17] and anti-inflammatory effect against LPS-induced ALI, as mentioned above [18, 19]. The gene discussed is DNM1L; the disease is lung disorder.