Recently, we found that YY1 could alter tumour cells metabolic reprogramming by regulating the transcription of key rate‐limiting enzymes, including GLUT3 and G6PD, which are crucial in glucose uptake and stimulation of the pentose phosphate pathway, as well as by regulating PGC‐1β, which is crucial for tumour cells lipid metabolism.42, 43, 44. This evidence concerns the gene G6PD and neoplasm.