DKK1 and rheumatoid arthritis: The Wnt1/β‐catenin signalling is known to be naturally suppressed by both LRP inhibitor (Dickkopf homolog 1 [DKK1]) and Dvl‐1 inhibitor (CYLD; a cell cycle regulator) that lead to the dormancy of β‐catenin inside the FLS cells, while are repressed in FLS cells during RA condition.60, 61, 62