The multivariate logistic analysis validated that EVA1A expression (OR = 2.199, 95% CI = 1.475‐3.278, P < .001), histological type (OR = 0.354, 95% CI = 0.221‐0.569, P < .001), disease stage (AJCC7; OR = 3.441, 95% CI = 2.240‐5.284, P < .001), tumour size (OR = 1.748, 95% CI = 1.099‐2.781, P = .018) and multi‐nodularity (OR = 1.535, 95% CI = 1.028‐2.292, P = .036) were significant and independent high‐risk factors of LNM (Table 5). This evidence concerns the gene EVA1A and neoplasm.