Tukey’s post hoc analysis showed that OPG levels were significantly high (p = 0.028) in class C, 4.356 (2.065) putting it under the umbrella of severe CLD as compared to class A, 2.832 (0.722) as shown in Table-II. This evidence concerns the gene TNFRSF11B and congenital secretory chloride diarrhea 1.