A few possible ways of involvement of omentin-1 in the MI process have been mentioned in the literature.14,15 Omentin- 1 upsurges insulin sensitivity, and insulin resistance is reflected as an imperative threat for subclinical atherosclerosis.14 A recent study proposed a defending role of omentin against endothelial dysfunction, and they described it directly supports endothelial role among subjects with diabetes and CVD risk factors.15 The gene discussed is ITLN1; the disease is Insulin resistance.