A few possible ways of involvement of omentin-1 in the MI process have been mentioned in the literature.14,15 Omentin- 1 upsurges insulin sensitivity, and insulin resistance is reflected as an imperative threat for subclinical atherosclerosis.14 A recent study proposed a defending role of omentin against endothelial dysfunction, and they described it directly supports endothelial role among subjects with diabetes and CVD risk factors.15 This evidence concerns the gene ITLN1 and endothelial dysfunction.