Nine of these 14 genes were previously suggested to be involved in malignant transformation, pathogenesis, progression, and immune microenvironment of GBM, including S100A9, HSPA1A, GALR2, EDNRB, IL13RA2, ELN, NR1D1, HDGF, and MET30–35. The gene discussed is NR1D1; the disease is glioblastoma.