Nine of these 14 genes were previously suggested to be involved in malignant transformation, pathogenesis, progression, and immune microenvironment of GBM, including S100A9, HSPA1A, GALR2, EDNRB, IL13RA2, ELN, NR1D1, HDGF, and MET30–35. This evidence concerns the gene IL13RA2 and glioblastoma.