AKR1B10 and hepatocellular carcinoma: Together, the serum levels of AKR1B10 before surgery was 1 163.968 ± 1 810.311 ng/mL, and the values decreased at the 1st day (950.524 ± 1 821.843 ng/mL) after surgery and declined nearly five-fold at the 5th day (228.837 ± 98.622 ng/mL) (P < 0.05; Fig. 6b and Supplementary Table S7), suggesting the specificity of serum AKR1B10 concentration for HCC.