PTPRZ1 and meningioma: To determine if genes underlying high ADC values were important for meningioma cell proliferation, we generated meningioma cells derived from the spatially-distinct sample M10G that stably expressed the CRISPRi components dCas9-KRAB56, and repressed CDH2 and PTPRZ1 by transducing cells with lentiviruses harboring sgRNAs against those genes (Fig. 6a).