To this end, we treated A549 and H1299 lung adenocarcinoma cells with doxorubicin and paclitaxel, two chemotherapeutic agents routinely used in the clinical treatment of lung cancer, and examined the changes in mRNA levels of USP29 along with those of three other DUBs (DUB3, OTUB1, and USP27X) reported to stabilize Snail1. This evidence concerns the gene USP29 and lung adenocarcinoma.