The difference in the relative number of CD4+ helper T cells between DLB and AD groups remained significant (mean difference 11.6 (95% CI 1.8–21.4), p=0.022) after correction for age and gender as possible confounders, as did the activation level of CD19+HLA-DR+ B cells (mean difference 13 164 (95% CI 4592–21736 standard units), p=0.003). Here, CD4 is linked to Alzheimer disease.