Interestingly, the expression of four (miR-193b-3p; miR-193b-5p; miR-2355-5p and miR-455-5p) out of six microRNAs targeting TMPRSS2 is higher in TP53 mutant HNSCC patients than in those with intact TP53 gene (Suppl. Here, TMPRSS2 is linked to head and neck squamous cell carcinoma.