AHA can occur abruptly in the postoperative period which strongly suggests that surgery was the trigger of acquired hemophilia A. The diagnosis often confirmed by a prolonged activated partial thromboplastin time (aPTT) and a low level of FVIII activity with evidence of the presence of FVIII inhibitor reported in Bethesda units (BU) [12, 13]. This evidence concerns the gene F8 and autoimmune hemolytic anemia.