Detailed coagulation workup showed aPTT of 78.1 s, FVIII activity 5% (normal 70–150%) FIX activity 67% (normal 70–120%), so the diagnosis was surgery associated acquired hemophilia A. FVIII and blood transfusion was given immediately but no bypassing agents or immunosuppressive therapy given. This evidence concerns the gene F8 and hemophilia A.