ALB and metastasis: Multivariable analysis showed that high PLR (> 148) (HR, 1.856 [95% CI, 1.266–2.723]; P = 0.002), low LMR (< 3.5) (HR 1.691 [95% CI, 1.023–2.797]; P = 0.041), distant LN metastasis (HR 1.929 [95% CI, 1.305–2.851]; P < 0.001), and low level of serum albumin (< 3.5 g/dL) (HR, 1.632 [95% CI, 1.017–2.618]; P = 0.043) were independent predictive factors of a short OS, after adjusting for alkaline phosphatase and ECOG PS.