Three antibodies, anti-Yo, anti-Tr, and anti-metabotropic glutamate receptor 1 (mGluR1), are predominantly associated with PCD, and several other antibodies, including anti-Hu, anti-Ma1, and anti-Ma2, have been reported in association with a variety of neurologic syndromes [2–4]. This evidence concerns the gene GRM1 and paraneoplastic neurologic syndrome.