SOD1 and amyotrophic lateral sclerosis: The sharing of important gene clusters between FUS and SOD1-ALS was also vigilant in the PPI network, with the hub genes showing the greatest commonality, justifying shared functions associated with the ribosome, RNA polymerase, circadian entrainment, Kaposi’s sarcoma-associated herpesvirus infection, the cell cycle, mitochondrial metabolic functions, p53 signaling and MAPK signaling pathways, reinforcing their demonstrated functions in ALS.