SOD1 and amyotrophic lateral sclerosis: We analyzed our gene expression datasets of iPSC-derived MNs at DIV 14 of terminal differentiation (=total DIV 30, Figure S1) since major structural degeneration appeared from DIV 16 of motor neuron differentiation (=total DIV 32) onwards [25], and compared them to the NCBI GEO GSE106382 [23] (FUS- and SOD1-ALS and controls) dataset contained data from ALS patients versus healthy controls (DIV35, also prior neurodegeneration became obvious).