A number of factors such as body mass index (BMI) (before and after pregnancy), weight gain during pregnancy, diagnosis of postpartum anemia and hemoglobin (Hb) value shortly after childbirth, diagnosis of hypothyroidism, TSH value, and hair cortisol concentration (HCC) at T0 and T1 were also considered, although none appeared to have any influence on RLS. The gene discussed is GSTM1; the disease is anemia.