As compared to controls, PV presented significantly higher levels of IL-1RA, IL-5, IL-6, IL-7, IL-12, IL-13, IFN-γ, GM-CSF, MIP-1α, MIP-1β, IP-10, MIG, VEGF, HGF, MCP-1, and IL-8 (these last three mediators are in common with Hermouet’s findings [64,65]), while EGF and CCL5 (or RANTES, Regulated on Activation, Normal T cell Expressed, and Secreted) were significantly reduced. The gene discussed is CCL4; the disease is acquired polycythemia vera.