The increased expression of RP11.259N19.1, KB.1460A1.5, and PP14571, along with low levels of PTEN-induced kinase 1 (PINK1) Antisense RNA (PINK1.AS), KLF3 antisense RNA 1 (KLF3.AS1), Long Intergenic Non-Protein Coding RNA 00,339 (LINC00339), LINC00472, Retinitis pigmentosa-11.351I21.11 (RP11.351I21.11), PKD1P6.NPIPP1, PDCD4 Antisense RNA 1 (PDCD4.AS1), KLF3 antisense RNA 1 (KLF3.AS1), PP14571, and RP11.69E11.4 were associated with an increased risk of recurrence in tamoxifen-resistant BC, and the 3/5 year survival rates further confirmed this in clinical cohorts. This evidence concerns the gene KLF3-AS1 and retinitis pigmentosa.