Subretinal delivery of normal gene using AAV2.1 (under the control of rhodopsin promoter) in Cngb1-null mice of autosomal recessive retinitis pigmentosa restored retinal morphology, CNGB1 channel expression, rod driven light responses in the retina, and delayed retinal degeneration [250,251]. Here, CNGB1 is linked to autosomal recessive retinitis pigmentosa.