HuR has high binding affinities for the 3′-UTRs of angiogenic factors (VEGF, COX-2, IL-8), an immunomodulating factor (IL-6), TGF-β, and TNF-α, and thus plays important roles in regulating tumor proliferation and angiogenesis in the central nervous system [166]. The gene discussed is VEGFA; the disease is neoplasm.