CCNB1 and neoplasm: TTP mainly functions as a tumor suppressor by targeting mRNAs encoding proteins related to the cell cycle (Cyclin B1 and D1), cell death and proliferation (Bcl-2 and cIAP), angiogenesis (VEGF), and EMT (Snail, Twist1, ZEB1, SOX9, MACC1, MMP2, MMP9, and IL-6) [103].