ARID1B and keratoconus: After confirming the successful knock down of Arid1b expression using short hairpin (pLK0-shARID1B) in both autochthonous and isogenic cells (Figure 7C,D), we found that only the “KAC” cell lines showed ≥ 80% decrease in cell proliferation, compared to “KC” or “KPC” control cells upon Arid1b knockdown (Figure 7E).