CD274 and neoplasm: The PD-L1 expression according to the combined positive score (CPS): tumor and TME cells, is predictive of the response rate (21% if CPS ≥ 1 vs. 6% if CPS < 1 p = 0.023) and of survival (median 10 months if CPS ≥ 1 vs. 5 months if CPS <1), whereas PD-L1 expression according to the tumor proportion score (TPS) which takes into account tumor cells only is not.