Lipopolysaccharide‐binding protein (LBP), sCD14, ubiquitin C‐like protein (UBC), ubiquitin thioesterase protein (OTUB1), transferrin receptor (TFRC), beta‐2‐microglobulin (B2M), cystatin (CST3) and FGA were up‐regulated in the MDR‐TB group and the DS‐TB group, compared with the HC group. The gene discussed is FGA; the disease is multidrug-resistant tuberculosis.