Lipopolysaccharide‐binding protein (LBP), sCD14, ubiquitin C‐like protein (UBC), ubiquitin thioesterase protein (OTUB1), transferrin receptor (TFRC), beta‐2‐microglobulin (B2M), cystatin (CST3) and FGA were up‐regulated in the MDR‐TB group and the DS‐TB group, compared with the HC group. Here, OTUB1 is linked to multidrug-resistant tuberculosis.