Although mRNA for both the co‐stimulatory molecule ICOS‐L and the co‐inhibitory molecule PD‐L1 were detected in healthy and inflamed cIECs of IBD patients, only low surface expression of ICOS‐L and PD‐L1 was detected in patient cIECs, with PD‐L1 being more highly expressed by cIECs in CD than in UC patients.69 The gene discussed is ICOSLG; the disease is inflammatory bowel disease.