In the same way, Eze et al. [13] conducted a cohort study on 6329 Swiss adults to examine the interaction of AP and genetic risk score, and they reported that the GRS of 63 SNPs did not significantly predict the incidence of type 2 diabetes for MTNR1B polymorphism (rs10830963). This evidence concerns the gene MTNR1B and type 2 diabetes mellitus.