Furthermore, we integrated the predicted target genes of miR-587 and the upregulated genes in HCC, and results showed that 13 differentially expressed target genes of miR-587 were found in HCC including OSR2, RAD54B, FAM81A, DKKL1, PTHLH, RPSA, ZNF781, ZNF92, CD163L1, ZNF138, PTPRR, TXNL4A, and ZNF124 (Figure 4(b)). This evidence concerns the gene PTHLH and hepatocellular carcinoma.