SOD1 and amyotrophic lateral sclerosis: To address the inconsistent data, meta-analyses have been performed; significant associations between Alzheimer's Disease (AD), Parkinson's Disease (PD), Amyotrophic Lateral Sclerosis (ALS), and blood oxidative stress markers were found, and these markers included MDA, 8-OHdG, SOD, and GPx [8–10].