Instead, we could only infer that the active ingredients contained in Compound-Xueshuantong Capsule had inhibitory effects on the AGE-RAGE signal pathway in diabetic complications, TNF signaling pathway, HIF-1 signaling pathway, and VEGF signaling pathway in diabetic retinopathy due to their effects on neovascularization, retinal edema, inflammatory response, and oxidative stress injury. This evidence concerns the gene HIF1A and diabetic retinopathy.