No significant association was observed between these two neoadjuvant treatment modalities and baseline clinicopathological features, namely age, sex, tumor size, clinical T status, clinical N status, vascular invasion, perineural invasion, clinical TNM stage, pretreatment serum CEA level, and posttreatment serum CEA level (Table 3, all P > 0.05). Here, CEACAM5 is linked to neoplasm.