Soybean-derived dipeptides and tripeptides decreased the colonic expressions of proinflammatory IFNG, IL-1B, IL-12B, TNF, and IL-17A and MPO activity and increased Foxp3 expression and CD4+CD25+ T cells; therefore, the colon and ileum inflammation of piglets with DSS-induced colitis was attenuated [74]. The gene discussed is TNF; the disease is colitis.