PDZK1IP1 and sarcoma: In order to look for a possible connection between MAP17 and DNA damage in sarcoma tumors, we decided to focus in pH2AX, due to the previously described role of pH2AX as a functional marker of DNA damage.42,44 To this end, we analyzed 69 samples from a cohort of different types of sarcomas for which we had clinical information52 (Supplementary Data Table S3).