MAP17 is a protein whose expression, in normal conditions, is limited only to kidney proximal tubule cells,62,63 increasing their expression during tumor progression.4,64 MAP17 could also be considered as a biomarker in tumors, since its high levels are associated with an increment in endogenous ROS,33,34,38 which induce DNA damage and DDR signaling.8 MAP17 correlations in sarcoma datasets (Fig. 1) allowed us to find a negative correlation between its expression and processes connected to DNA repair, suggesting a possible functional connection between MAP17 and DNA damage repair. This evidence concerns the gene PDZK1IP1 and neoplasm.