ERG and neoplasm: By integrating genetic and transcriptomic information matched to the same samples (using the TCGA database) a higher proportion of tumor samples showed significantly increased ERG expression (Z-score > 2) relative to down-regulation (Z-score < −2) (Fig. 3A), in line with the observed higher proportion of samples with ERG amplifications than with deletions (Figs. 2A, 3A).