GPT and coinfection: Our previous systematic review and meta-analysis demonstrated that malaria parasitaemia, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels in DENV and Plasmodium co-infection were lower than those in Plasmodium mono-infection, while the platelet count and haemoglobin levels were significantly higher in patients with co-infections [19].