Moreover, it has been reported that the expression of the full-length NK-1R was inversely correlated with lymph-node metastasis and tumor-lymph-node metastasis [65] and that SP/NK-1R expression may be used as a predictor for the prognosis of colorectal cancer [75]. The gene discussed is TACR1; the disease is metastatic malignant neoplasm in the lymph nodes.