CDH17 and neoplasm: In more detail, oral fusobacterium nucleatum, which is abundant in the oral cavity and increased in periodontal pockets, is mobile and caplable to bind, through the Fusobacterium adhesin A (FadA), both to vascular endothelial-cadherins, gaining access to systemic circulation, and to (E)-cadherin on epithelial cells, stimulating the growth of tumor cells.