Tumors were classified as “immune excluded” if at least five-fold more CD8+ cells were present in the tumor margin compared to the tumor center, “immune desert” if they were not “excluded” but still had below the 25th percentile of CD8+ cells in the tumor center, and “immune infiltrate” if they were not “excluded” and had greater than the 25th percentile of CD8+ cells in the tumor center. Here, CD8A is linked to neoplasm.