SOD1 and Ureteral obstruction: Our results are in agreement with previous studies reporting that the secoiridoid oleuropein, a major component of olive polyphenols, increased the levels of SOD and GSH-Px in gentamicin-induced renal toxicity and in cisplatin-induced renal injury models [62,81,82], as well as in the kidneys of rats with unilateral ureteral obstruction [83].