The shifts in the cytokine panel are differently associated with the patterns of CKD: IL-17A and MIP-1α are predictors of non-albuminuric CKD, IL-13 is associated with the pattern of albuminuria and preserved renal function; meanwhile, IL-6 and hs-CRP could be predictors of albuminuria with eGFR decline. This evidence concerns the gene IL6 and chronic kidney disease.