SARS-CoV infection induces upregulation of proinflammatory cytokines/chemokines, such as interleukin (IL)-1β, IL-6, IL-8, IL-12, monocyte chemotactic protein 1 (MCP-1), and IFN-γ inducible protein (IP-10), in the tissues and serum during the first two weeks of illness onset [73]. This evidence concerns the gene CCL2 and severe acute respiratory syndrome.