Zhang et al. (2019) reported a down-regulation of miR-1 in BCSC and it triggered mitophagy of cancer stem cells by binding to the LRPPRC protein and targeting mitochondrial inner membrane organizing system 1 (MINOS1) and glycerol-3-phosphate dehydrogenase 2 (GPD2) mRNAs [82]. This evidence concerns the gene GPD2 and cancer.