TNF and prostate carcinoma: The anti-inflammatory and immunomodulatory effects of flavonol-rich (quercetin and quercetin-4′-O-glucoside) red onion scale extract on prostate cancer rat model are observed by the suppressed expressions of pro-inflammatory molecules including interleukin (IL)-6, IL-8, and tumor necrosis factor-alpha (TNF-α) in prostatic tissues [14].