IGHE and congenital rubella syndrome: Clusters are identified based on analysis of IL-5, IFN-γ, IL-17A, TNF-α, IL-22, IL-1β, IL-6, IL-8, cationic eosinophilic protein, myeloperoxidase, TGF-β1, IgE, staphylococcus aureus-specific IgE for enterotoxin, and albumin in CRS in the nose itself and are highly modified with the disease [2,5].