To analyze the effects of p53 activation and genotoxic stress on cell growth, human MM cell lines expressing wild‐type p53 protein (MESO4, 211H, and H28) [28] or with TP53 loss (MESO1) [28] were treated with nutlin‐3a (10 μm) or Dox (a nongenotoxic and a genotoxic p53 activator, respectively) for 24 h. This evidence concerns the gene TP53 and Miyoshi myopathy.