Compared with H7;Lats1/2mut3 mice, H7;Lats1/2mut3;YAP/TAZmut4, H7;Lats1/2mut3;YAP/TAZmut3, and H7;Lats1/2mut3;YAP/TAZmut2 mice exhibited a YAP/TAZ dosage–dependent increase in time to tumor onset and decrease in tumor number (Figure 4, A and B). Here, LATS1 is linked to neoplasm.