Various studies have confirmed the correlation between lncRNAs and EMT key effectors during carcinogenesis: Zheng et al28 revealed that lncRNA PVT1 can regulate the invasion of esophageal cancer cells by inducing EMT; Zhang et al29 proposed that lncRNA PVT1 may play an oncogenic role by regulating EMT through the TGFβ/Smad pathway in pancreatic cancer. Here, PVT1 is linked to esophageal cancer.